Indication
The indications are based on the anti-parasitic and antibacterial activity, and on the pharmacokinetic characteristics of Metronidazole. They are restricted to infections caused by the microorganism defined previously as susceptible to Metronidazole:
- Amoebiasis
- Urogenital trichomoniasis
- Non specific vaginalis
- Giardiasis
- Curative treatment of medico-surgical infections due to susceptible anaerobic pathogens.
- Prophylaxis against infections caused susceptible anaerobic pathogens in high risk surgical contents.
- Conversion from prophylactic or curative injectable treatment of infections due to susceptible anaerobic pathogens.
Metronidazole is also indicated in the treatment of trichomoniasis in both male and female patients when the presence of trichomonas has been demonstrated by wet smear or culture and for sexual partners of those patients who have recurrence of infections. Trichomonal infection is demonstrated for other protozoa including Entamoeba histolytica, giardiasis and liver abscess.