Indication
Treatment of the following conditions in children and adults (culture and susceptibility testing should be done): Upper respiratory tract infections of mild to moderate severity caused by Streptococcus pyogenes, viridans group streptococci, Streptococcus pneumoniae or Haemophilus influenzae (when erythromycin is used concomitantly with adequate doses of sulfonamides, since not all strains of H. influenzae are susceptible at the erythromycin concentrations ordinarily achieved). Lower respiratory tract infections of mild to moderate severity caused by S. pyogenes, S. pneumoniae, Mycoplasma pneumoniae or Legionella pneumophila. Primary syphilis caused by Treponema pallidum. Erythromycin is an alternate choice of treatment for primary syphilis in penicillin-allergic patients. In primary syphilis, spinal fluid examination should be done before treatment and as part of follow up after therapy. Diphtheriae: As an adjunct to antitoxin, to prevent establishment of carriers and to eradicate the organism in carriers. Erythrasma: In the treatment of infections due to Corynebacterium minutissimum. Intestinal amebiasis caused by Entamoeba histolytica. Extraenteric amebiasis requires treatment with other agents. Infections due to Listeria monocytogenes. Skin and soft tissue infections of mild to moderate severity caused by S. pyogenes or Staphylococcus aureus (resistant staphylococci may develop during treatment). Pertussis Caused by Bordetella pertussis. Conjunctivitis of the newborn, pneumonia of infancy and urogenital infections during pregnancy caused by Chlamydia trachomatis. When tetracyclines are contraindicated or not tolerated, erythromycin is indicated for the treatment of adults with uncomplicated urethral, endocervical or rectal infections due to C. trachomatis.
